HLA TIZIMI GENLARI POLIMORFIZMINING ABORT RIVOJLANISHIDAGI ROLI
Abstract
Ushbu maqola insonning HLA (Gistogomologik antigenlar) tizimiga oid genlarining polimorfizmi va bu genetik o‘zgaruvchanlikning homiladorlikdagi patologik holat, xususan, spontanne abort (RSA) rivojlanishidagi roli haqida ilmiy sharh beradi. HLA-G, HLA-E, HLA-DQ kabi genlarning immunologik tolerantlikdagi funksiyasi, ularning allel o‘zgarishlari va embrionni immun tan olinmasligiga olib keluvchi mexanizmlar tahlil qilinadi.
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