SUBSTANCES AFFECTING THE HEART AND VASCULAR SYSTEM
Abstract
Substances affecting the heart and vascular system include a diverse group of pharmacological agents that influence cardiovascular function. These substances can modify heart rate, contractility, blood pressure, and vascular tone, thereby playing a crucial role in managing cardiovascular diseases such as hypertension, heart failure, arrhythmias, and ischemic heart conditions. They include positive and negative inotropes, vasodilators, vasoconstrictors, antiarrhythmics, and diuretics. Understanding the mechanisms, therapeutic uses, and potential side effects of these agents is essential for effective cardiovascular treatment and patient management.
References
1. Katzung, B. G., Masters, S. B., & Trevor, A. J. (2018). Basic & Clinical Pharmacology (14th ed.). McGraw-Hill Education. Comprehensive source covering cardiovascular pharmacology, including drug classes affecting heart and vessels.
2. Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J., & Henderson, G. (2015). Rang & Dale's Pharmacology (8th ed.). Elsevier Health Sciences. Detailed explanation of drugs influencing cardiac and vascular function.
3. Brunton, L. L., Hilal-Dandan, R., & Knollmann, B. C. (2017). Goodman & Gilman’s The Pharmacological Basis of Therapeutics (13th ed.). McGraw-Hill Education.