HYPERTENSION AND ITS PATHOGENESIS

Authors

  • Marufova Mohigul O‘ktamovna Pediatrician, Jomboy Health Department
  • Ruziyeva Zilola Shavkatjonovna Student, Samarkand State Medical University

Abstract

This article analyzes the anatomical and morphological changes of the heart that occur in the context of hypertension. Prolonged elevation of arterial blood pressure leads to structural remodeling of the heart, particularly left ventricular hypertrophy and myocardial thickening. Structural alterations also develop in the atrial and ventricular cavities, affecting the functional activity of the heart. The article compares normal cardiac anatomy with pathological changes and explains their pathogenetic mechanisms. The findings highlight the importance of anatomical knowledge in the early detection of hypertension and prevention of its complications.

References

1. World Health Organization. Clinical guidelines and statistical data on arterial hypertension.

2. Harrison’s Principles of Internal Medicine. Section on arterial hypertension.

3. Guyton and Hall Textbook of Medical Physiology. Blood pressure regulation and the renin–angiotensin system.

4. Frolov, V. A., & Chumakov, A. G. (Eds.). Pathological Physiology. Section on hypertension pathogenesis.

5. European Society of Cardiology. Guidelines for the diagnosis and treatment of arterial hypertension.

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Published

2026-02-19

Issue

Vol. 3 No. 2 (2026): Ensuring the integration of science and education on the basis of innovative technologies.

Section

Articles