MOOD AND BEHAVIORAL CHANGES AFTER DEEP BRAIN STIMULATION IN A PATIENT WITH PARKINSON’S DISEASE: A CASE REPORT
Abstract
Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for advanced Parkinson’s disease (PD), improving motor function in patients with inadequate response to medication. However, neuropsychiatric and behavioral complications may occur postoperatively.
References
1. Temel Y., Kessels A., Tan S., Topdag A., Boon P., Visser-Vandewalle V. (2006). Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: a systematic review. Parkinsonism & Related Disorders, 12(5), 265–272.
2. Mallet L., Schüpbach M., N'Diaye K. et al. (2007). Stimulation of subterritories of the subthalamic nucleus reveals its role in the integration of emotional and motor behavior. PNAS, 104(25), 10661–10666.
3. Voon V., Krack P., Lang A.E., Lozano A.M., Dujardin K., Schüpbach M., et al. (2008). A multicentre study on personality changes following subthalamic stimulation in Parkinson’s disease. Brain, 131(10), 2638–2648.
4. Mosley P.E., Marsh R., Coyne T. (2015). Deep brain stimulation and its neuropsychiatric effects: Implications for neurologists and psychiatrists. Journal of Neurology, Neurosurgery & Psychiatry, 86(12), 1407–1415.
5. Okun M.S., Foote K.D. (2010). Parkinson’s disease DBS: What, when, who and why? The time has come to tailor therapy individually. Expert Review of Neurotherapeutics, 10(12), 1847–1857.
