CLINICAL OUTCOMES OF EARLY NECRECTOMY AND AUTODERMOPLASTY IN PATIENTS WITH DEEP BURN INJURIES

Abstract

Deep burn injuries remain one of the most severe forms of thermal trauma, characterized by extensive tissue necrosis, profound inflammatory response, and a high risk of infectious complications. The presence of devitalized tissues creates favorable conditions for microbial colonization, persistent inflammation, and systemic intoxication, which significantly worsen clinical outcomes and prolong hospitalization. In patients with deep burns, delayed wound closure is associated with increased morbidity, higher incidence of sepsis, metabolic disturbances, and unsatisfactory functional and cosmetic results.  For many years, the management of deep burn wounds was based on a conservative or delayed surgical approach, allowing spontaneous demarcation of necrotic tissues before surgical intervention.