GEPATIT B VA C NINGUZOQ MUDDATLI ASORATLARI: GEPATOSITLAR VA JIGAR SIRROZI XAVFI VA OQIBATLARI
Abstract
Ushbu maqolada surunkali B va C gepatit viruslarining gepatositlarga (jigar hujayralariga) ko‘rsatadigan patogen ta’siri va bu jarayonning jigar sirroziga aylanish mexanizmlari batafsil tahlil qilinadi. Tadqiqotda gepatotsitlar ichidagi virusli replikatsiyaning hujayra metabolizmiga ta’siri, oksidativ stress va surunkali yallig‘lanish natijasida kelib chiqadigan fibroz bosqichlari ko‘rib chiqiladi. Shuningdek, maqolada gepatit B va C ning uzoq muddatli oqibatlari, jumladan, jigar yetishmovchiligi, portal gipertenziya va gepatotsellyulyar karsinoma (jigar saratoni) rivojlanish xavfi statistik ma’lumotlar asosida yoritilgan. Xulosa qismida zamonaviy diagnostika usullari va virusga qarshi terapiyaning asoratlarni kamaytirishdagi roli haqida tavsiyalar berilgan.
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