GLOBAL DISTRIBUTION OF ORPHAN DISEASES BY GEOGRAPHIC REGIONS AND PREVENTIVE STRATEGIES
Abstract
Orphan diseases, also known as rare diseases, affect a small proportion of the population individually but collectively impose a substantial global health burden. Their prevalence varies significantly across geographic regions due to genetic, environmental, demographic, and healthcare-related factors. This review analyzes the global distribution of orphan diseases by regions and discusses current preventive strategies, including early diagnosis, genetic counseling, and public health interventions. Understanding regional patterns is essential for improving prevention, diagnosis, and equitable healthcare access worldwide.
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