DYNAMICS OF SERUM GLUCOSE, INSULIN, CORTISOL AND HBA1C AND JOINT MORPHOLOGY IN RATS WITH ALLOXAN-INDUCED DIABETES

Abstract

Diabetes mellitus is a complex metabolic disorder characterized by disturbances in carbohydrate metabolism and hormonal imbalance, which can lead to structural and functional changes in various organs and tissues. Experimental models using alloxan-induced diabetes in laboratory animals are widely applied to investigate the mechanisms of metabolic disorders and their systemic effects.