MOLECULAR-GENETIC DETERMINANTS OF IRON METABOLISM DISORDERS IN SCHOOLCHILDREN OF THE FERGANA VALLEY AND SYSTEMATIC ANALYSIS OF THEIR PREDICTIVE VALUE
Abstract
Iron deficiency anemia (IDA) is a common diet-related disorder among school-aged children, leading to impaired physical growth, cognitive development, and immune system function. Scientific evidence indicates that 20–30% of the variability in serum iron levels is determined by genetic factors. Recent large-scale genomic studies have shown that polymorphisms in the TMPRSS6 gene, which regulates iron homeostasis, are associated with hemoglobin levels and erythrocyte indices.


