HEMATOLOGICAL DISORDERS AMONG SCHOOLCHILDREN IN THE FERGANA VALLEY - PREVALENCE, AGE-DEPENDENT DYNAMICS, AND PREVENTIVE IMPLICATIONS
Abstract
This thesis investigates the prevalence and age-specific dynamics of diseases of the blood and blood-forming organs - predominantly iron deficiency anemia - among schoolchildren in the Fergana Valley. Data from three regional cohorts spanning 2013-2023 were analyzed using comparative epidemiological methods. The findings reveal that hematological pathologies constitute the leading nosological category across all age groups, with peak rates in adolescence. Early molecular-genetic screening and nutritional correction are substantiated as cost-effective preventive measures with significant public health implications.
References
1. Cortés-Ramírez J., Wilches-Vega J.D., Pineda O.M.P., Rod J.E., Sly P.D. Environmental risk factors associated with respiratory diseases in children with socioeconomic disadvantage // Heliyon. - 2021. - Vol. 7, No. 4. - e06820. - DOI: 10.1016/j.heliyon.2021.e06820.
2. Abdurakhmonov G.M., Gasangadzhieva A.G., Daudova M.G., Gabibova P.I., Salimkhanov N.G. Geographical distribution of socially significant and ecology-dependent morbidity of the population of the Untsukul district // South of Russia: Ecology, Development. - 2018. - Vol. 13, No. 1. - P. 128-144. - DOI: 10.18470/1992-1098-2018-1-128-144.
3. Hassen H.Y., Govarts E., Rémy S., Cox B., Iszatt N., Portengen L., Covaci A., Schoeters G. Association of environmental pollutants with asthma and allergy, and the mediating role of oxidative stress and immune markers in adolescents // Environmental Research. - 2024. - Vol. 265. - 120445. - DOI: 10.1016/j.envres.2024.120445.
