PERSONALIZED MEDICINE: TREATMENTS BASED ON GENETIC INFORMATION.
Abstract
This article reviews personalized medicine and genetic data-based treatment methods. Personalized medicine allows for the development of individual treatment strategies based on a patient's genetic profile, biomarkers, and clinical data. The article reviews in detail the theoretical foundations of personalized medicine, the role of genetic testing and pharmacogenomics, and their application in clinical practice. At the same time, the advantages, limitations, and development prospects of this approach using modern technologies are analyzed. The article is enriched with examples from the fields of oncology, cardiology, pharmacology, and infectious diseases, demonstrating the importance of personalized medicine in improving patient health and effectively using medical resources.
References
1. Collins, F. S., & Varmus, H. (2015). A new initiative on precision medicine. New England Journal of Medicine, 372(9), 793–795. https://doi.org/10.1056/NEJMp1500523
2. Ashley, E. A. (2016). The precision medicine initiative: A new national effort. JAMA, 315(8), 793–794. https://doi.org/10.1001/jama.2016.0297
3. Hamburg, M. A., & Collins, F. S. (2010). The path to personalized medicine. New England Journal of Medicine, 363(4), 301–304. https://doi.org/10.1056/NEJMp1006304
4. Manolio, T. A., Chisholm, R. L., Ozenberger, B., Roden, D. M., Williams, M. S., Wilson, R., … Ginsburg, G. S. (2013). Implementing genomic medicine in the clinic: The future is here. Genetics in Medicine, 15(4), 258–267. https://doi.org/10.1038/gim.2012.157
5. Schork, N. J. (2015). Personalized medicine: Time for one-person trials. Nature, 520(7549), 609–611. https://doi.org/10.1038/520609a
